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Scabo 12 is prescribed for the treatment of various parasitic infections, including:
- Strongyloidiasis (intestinal infections by Strongyloides stercoralis)
- Onchocerciasis (Onchocerca volvulus infections)
- Filariasis
- Scabies
- Pediculosis capitis (head lice)
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✅ Description:
Ivermectin acts by binding with high affinity to glutamate-gated chloride channels present in invertebrate nerve and muscle cells. This interaction increases the influx of chloride ions, resulting in hyperpolarization, paralysis, and death of the parasite.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Common Side Effects:
Mild burning, stinging, or tingling at the application site
These are typically mild and temporary.
✔️ Precautions:
- Inform your doctor if you have existing skin conditions, asthma, or known allergies to medicines, foods, or topical products.
- Consult a healthcare provider before using this product if you are pregnant or breastfeeding, even though it is generally considered safe.
✔️ Uses
- Parasitic infections
✔️ Dosage & Administration
For Strongyloidiasis:
Single oral dose of 200 mcg/kg of body weight.
Stool exams may be repeated to confirm eradication.
| Body Weight (kg) | Ivermectin Dose |
|---|---|
| 15–24 | 3 mg |
| 25–35 | 6 mg |
| 36–50 | 9 mg |
| 51–65 | 12 mg |
| 66–79 | 15 mg |
| >80 | 200 mcg/kg |
For Onchocerciasis:
Single oral dose of 150 mcg/kg.
Re-dosing may be required every 3–12 months based on clinical response.
| Body Weight (kg) | Ivermectin Dose |
|---|---|
| 15–25 | 3 mg |
| 26–44 | 6 mg |
| 45–64 | 9 mg |
| 65–84 | 12 mg |
| >85 | 150 mcg/kg |
COVID-19 Off-label Use (not a standard indication):
Treatment: Ivermectin 6 mg × 2 tablets daily for 5 days.
Prophylaxis: Same dose on Day 1 and Day 7 based on weight.
- Children <15 kg: Safety and efficacy not established.
- Elderly (65+): Limited data; no specific adjustments unless clinically indicated.
✔️ Administration
- Take the tablet whole with water on an empty stomach.
- Avoid caffeine and drink plenty of fluids for optimal absorption.
- Always follow your physician’s instructions regarding dosage and treatment duration.
✔️ Drug Interactions
Warfarin: Rare cases of elevated INR reported; monitor coagulation parameters if co-administered.
✔️ Contraindications
Known hypersensitivity to Ivermectin or any component of the formulation.
✔️ Side Effects
Common:
- Application site burning (when applied topically)
Systemic (Oral):
Strongyloidiasis:
- Dizziness, somnolence
- GI upset: nausea, diarrhea, abdominal pain
- Rash, pruritus
- Fatigue
- Onchocerciasis:
- Pruritus, rash, joint pain
- Lymph node swelling/tenderness
- Eye symptoms (rarely severe): uveitis, conjunctivitis
- Fever, hypotension, asthma worsening (rare)
- Severe skin reactions (e.g., Stevens-Johnson Syndrome – rare)
✔️ Warnings
- Mazzotti Reaction: In patients with onchocerciasis, allergic/inflammatory reactions may occur due to parasite death, including fever, rash, hypotension, and lymphadenopathy.
- Loa loa co-infection: Risk of severe or fatal encephalopathy in heavily infected individuals.
- Avoid use in pregnancy unless necessary. Not enough studies are available to ensure safety.
- Lactation: Excreted in low levels in breast milk; use only if benefits outweigh risks.
✔️ Storage
- Store in a cool, dry place below 30°C.
- Protect from light and keep out of children’s reach.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
